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产品目录

Caspase 9/CASP9抗体图片
产品货号:
Z12729
中文名称:
Caspase 9/CASP9抗体
英文名称:
Anti-Caspase 9/CASP9 Antibody
产品规格:
100μg(vial)
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Caspase 9/CASP9 Antibody
指标别名APAF 3;APAF3;Apoptotic protease Mch 6;CASP 9;CASP9;Caspase 9;Caspase 9/p35/p10;CASPASE 9c;Caspase9;Caspase-9;ICE LAP6;ICE like apoptotic protease 6;MCH6
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称CASP9
抗体来源Rabbit
抗体类型IgG
免疫原Recombinant human procaspase-9 (N-terminal fragment).
计算分子量46kDa
成分Each vial contains 0.09% sodium azide.
纯化方式Protein A affinity purified.
浓度0.5~1mg/mL,actual concentration vary by lot.Use suggested dilution ratio to decide dilution procedure.
产品形态溶液
背景资料CASP9 (CASPASE9),also called APAF3,is an initiator caspase,encoded by the CASP9 gene.The CASP9 gene is mapped to chromosome 1p36.3-p36.1 by FISH.CASP9 is identified as a member of the caspase family that participates in caspase-3 activation in vitro.And it also regarded as the most upstream member of the apoptotic protease cascade that is triggered by cytochrome c and dATP.Its genomic coordinates (GRCh37) is 1:15,818,768-15,851,284.The crystal structure of CASP9 is complex with the BIR3 in an inhibitory domain of XIAP at 2.4-angstrom resolution and the CASP9 gene contains 9 exons and spans approximately 35kb of genomic DNA.Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome c and dATP,an event that leads to caspase-9 activation.CASP9 activity increases dramatically upon association with the apoptosome complex.And the majority of Casp9 knockout mice died perinatally with a markedly enlarged and malformed cerebrum caused by reduced apoptosis during brain development.
Uniprot IDP55211
基因名全称Caspase-9
蛋白名全称Caspase-9 (CASP9)
推荐稀释比WB,1:500,ECL,Human,Mouse,Rat

相关搜索:Caspase 9/CASP9抗体Caspase 9抗体CASP9多抗Anti-Caspase 9/CASP9 Antibody
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